Semaglutide
Have you lost weight in the past only to have it return? Semaglutide may be able to help you lose weight and keep it off.
For adults with obesity or some adults with excess weight and weight-related medical problems, along with a reduced calorie meal plan and increased physical activity
Who can take Semaglutide?
People living with obesity (BMI ≥30)
Living with excess weight (BMI ≥27) and weight-related medical problems (such as high blood pressure or high cholesterol)
What Is Semaglutide (GLP-1)?
Semaglutide is an FDA-approved weight loss injection. It works by mimicking a hormone in the body, Semaglutide increases insulin secretion while slowing down how fast your stomach empties food. This suppresses your appetite, so you feel full longer, helping you eat less and lose weight. Brand names of this product include Wegovy, Saxenda, Ozempic, among others.
GLP-1 is a physiological regulator of appetite and caloric intake, and the GLP-1 receptor is present in several areas of the brain involved in appetite regulation. The human body naturally produces the GLP-1 hormone when there is food in the stomach, reducing appetite while lowering blood sugars at the same time.
Dosing Semaglutide 2.5mg/mL 5mL vial
Month 1: 0.25mg weekly Inject: 0.1mL
Month 2: .5mg weekly Inject: 0.2mL
Month 3: 1mg weekly Inject: 0.4mL
Month 4: 1.5mg weekly Inject: 0.6mL
Month 5: 2mg weekly Inject: 0.8mL
Month 6: 2.5mg weekly Inject 1mL
The maintenance dose for Semaglutide is 2.5mg Some patients find that the 1mg dose works well for them and may choose to stay on this dose. This is the same with the 2mg dose. You can discuss your weight loss results with your provider at any time using our patient portal to decide what is best for you.
Revised 8/21/2023
What are the possible side effects of Semaglutide?
The most common side effects of Semaglutide may include:
nausea
diarrhea
vomiting
constipation
stomach (abdomen) pain
headache
tiredness (fatigue)
upset stomach
dizziness
feeling bloated
belching
gas
stomach flu
heartburn
runny nose
sore throat
Semaglutide may cause serious side effects, including:
inflammation of your pancreas (pancreatitis). Stop using Semaglutide and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back
gallbladder problems. Semaglutide may cause gallbladder problems, including gallstones. Some gallstones may need surgery. Call your healthcare provider if you have symptoms, such as pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), or clay-colored stools
increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes, especially those who also take medicines for type 2 diabetes such as sulfonylureas or insulin. This can be both a serious and common side effect. Talk to your healthcare provider about how to recognize and treat low blood sugar and check your blood sugar before you start and while you take Semaglutide. Signs and symptoms of low blood sugar may include dizziness or light-headedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, or feeling jittery
kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse. It is important for you to drink fluids to help reduce your chance of dehydration
serious allergic reactions. Stop using Semaglutide and get medical help right away, if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat
change in vision in people with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with Semaglutide
increased heart rate. Semaglutide can increase your heart rate while you are at rest. Tell your healthcare provider if you feel your heart racing or pounding in your chest and it lasts for several minutes
depression or thoughts of suicide. You should pay attention to any mental changes, especially sudden changes in your mood, behaviors, thoughts, or feelings. Call your healthcare provider right away if you have any mental changes that are new, worse, or worry you